Medical Laboratory Scientist (MLS) ASCP Exam 2025 – 400 Free Practice Questions to Pass the Exam

Question: 1 / 400

Hemophilia B is caused by a deficiency in which coagulation factor?

Factor VIII

Factor IX

Hemophilia B is specifically caused by a deficiency in Factor IX. This genetic disorder leads to reduced ability for blood to clot properly. Individuals with Hemophilia B often experience prolonged bleeding episodes, particularly after injuries or surgeries. The deficiency in Factor IX affects the intrinsic pathway of the coagulation cascade, ultimately resulting in inadequate thrombin formation and fibrin clot stabilization.

Factor VIII is associated with Hemophilia A, which is different from Hemophilia B. Factor X and Factor XI are involved in other coagulation processes but are not directly responsible for Hemophilia B. Thus, the indication that a deficiency in Factor IX leads to Hemophilia B distinguishes this condition clearly from the other factors mentioned. This understanding is crucial for both diagnosis and treatment management in individuals with this bleeding disorder.

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Factor X

Factor XI

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