Medical Laboratory Scientist (MLS) ASCP Exam 2025 – 400 Free Practice Questions to Pass the Exam

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What type of inclusion are Heinz bodies?

Denatured hemoglobin inclusions

Heinz bodies are indeed classified as denatured hemoglobin inclusions. These structures represent aggregated hemoglobin that has undergone denaturation, primarily due to oxidative stress. In clinical practice, their presence is often associated with conditions such as glucose-6-phosphate dehydrogenase (G6PD) deficiency, various types of hemolytic anemia, and exposure to certain toxins or drugs.

Denatured hemoglobin tends to form these inclusions within red blood cells, leading to potential membrane instability and subsequent hemolysis. Their detection is typically performed via special staining techniques such as the crystal violet stain or the methylene blue stain, which can highlight these inclusions, allowing for better diagnosis and understanding of the underlying condition.

The other options do not correctly describe Heinz bodies; rather, they refer to different types of cellular structures or conditions unrelated to the denaturation of hemoglobin. Understanding the correct identification of Heinz bodies is essential for diagnosing conditions that result from oxidative damage to red blood cells.

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Normal hemoglobin inclusions

Immature red blood cells

Platelet aggregates

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