Medical Laboratory Scientist (MLS) ASCP Exam 2025 – 400 Free Practice Questions to Pass the Exam

The antigen found with the highest frequency in the Caucasian population is e. In the context of blood group antigens, the Rh system is notable for its complexity, comprising several antigens, with D, C, E, c, and e being the most clinically significant. The e antigen, specifically, has one of the highest prevalence rates among Caucasians, often observed in greater than 98% of this population.

Understanding the distribution of Rh antigens among different ethnicities is crucial for blood transfusions and organ transplants, as matching donors and recipients can prevent hemolytic reactions. This knowledge aids in predicting compatibility and planning for transfusions, which is particularly important in clinical settings.

In contrast, the other antigens listed (C, E, and c) have lower frequencies when specifically considering the Caucasian demographic, making them less relevant in this particular context. The C and E antigens are less prevalent compared to e, while the c antigen, although somewhat common, does not match the high occurrence of e. Thus, recognizing e as the most frequent Rh antigen in Caucasians is essential for applying this information in transfusion practices.